From the DeSmuME FAQ:
DeSmuME is a Nintendo DS emulator and the name is a play of words - DS Emu + ME.
If you're looking for the newest Nintendo DS emulator for Mac, you've come to the right place! ConsoleEmu.com is your source for the latest builds of DeSmuME for Mac OS X (10.7+). Coming soon!
FAQ (+ documentation): http://wiki.desmume.org/index.php?title=Faq
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